1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one
TL;DR: 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one (CAS 585553-33-9) is a chemical compound with molecular formula C23H20N2O4S and molecular weight 420.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy-(4-methoxyphenyl)methylidene]-5-phenylpyrrolidine-2,3-dione
Also Known As: 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one, (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-phenylpyrrolidine-2,3-dione, (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy-(4-methoxyphenyl)methylidene]-5-phenylpyrrolidine-2,3-dione, 1-(4,5-dimethyl(1,3-thiazol-2-yl))-3-hydroxy-4-[(4-methoxyphenyl)carbonyl]-5-p henyl-3-pyrrolin-2-one
| Molecular Formula | C23H20N2O4S |
|---|---|
| Molecular Weight | 420.11 g/mol |
| LogP | 4.39484 |
| Topological Polar Surface Area | 79.73 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 420.11438 |
| Heavy Atoms | 30 |
| Complexity | 1130.206 |
Chemical Identifiers
| CAS Number | 585553-33-9 |
|---|---|
| SMILES | CC1=C(SC(=N1)N2C(/C(=C(/C3=CC=C(C=C3)OC)\O)/C(=O)C2=O)C4=CC=CC=C4)C |
Product Overview
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one (CAS 585553-33-9), with molecular formula C23H20N2O4S and molecular weight 420.11 g/mol. IUPAC: (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy-(4-methoxyphenyl)methylidene]-5-phenylpyrrolidine-2,3-dione.
Chemical Property Profile of 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one
Property Insights of 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one
The XLogP value of 4.39484 indicates that 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.73 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one. Following Lipinski's Rule of Five, 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one?
The CAS number of 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one is 585553-33-9.
What is the molecular formula of 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one?
The molecular formula of 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one is C23H20N2O4S.
What is the molecular weight of 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one?
The molecular weight of 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one is 420.11 g/mol.
Where can I buy 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one?
You can request a quote for 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methoxybenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.