![(5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one structure](/static/products/585/585553-32-8.png)
(5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one
TL;DR: (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one (CAS 585553-32-8) is a chemical compound with molecular formula C20H17ClN4O3S and molecular weight 428.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(2-chlorophenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one
Also Known As: (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one, (Z)-5-(2-chlorobenzylidene)-2-(4-(2-nitrophenyl)piperazin-1-yl)thiazol-4(5H)-one, 5-[(2-chlorophenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one, (5Z)-5-[(2-chlorophenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one
| Molecular Formula | C20H17ClN4O3S |
|---|---|
| Molecular Weight | 428.07 g/mol |
| LogP | 4.0407 |
| Topological Polar Surface Area | 79.05 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 428.07098 |
| Heavy Atoms | 29 |
| Complexity | 1031.8914 |
Chemical Identifiers
| CAS Number | 585553-32-8 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2[N+](=O)[O-])C3=NC(=O)/C(=C/C4=CC=CC=C4Cl)/S3 |
Product Overview
(5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one (CAS 585553-32-8), with molecular formula C20H17ClN4O3S and molecular weight 428.07 g/mol. IUPAC: (5Z)-5-[(2-chlorophenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one.
Chemical Property Profile of (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one
Property Insights of (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one
The XLogP value of 4.0407 indicates that (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.05 Ų falls within the moderate polarity range, balancing permeability and solubility for (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one. Following Lipinski's Rule of Five, (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
The CAS number of (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one is 585553-32-8.
What is the molecular formula of (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
The molecular formula of (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one is C20H17ClN4O3S.
What is the molecular weight of (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
The molecular weight of (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one is 428.07 g/mol.
Where can I buy (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
You can request a quote for (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (5Z)-5-(2-chlorobenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.