7H-Purine-8-thiol structure

7H-Purine-8-thiol

TL;DR: 7H-Purine-8-thiol (CAS 583-40-4) is a chemical compound with molecular formula C5H4N4S and molecular weight 152.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7,9-dihydropurine-8-thione

Also Known As: 7H-Purine-8-thiol, 8-Mercaptopurine, Purine-8-thiol, 7,9-dihydropurine-8-thione, 9H-purine-8-thiol

CAS: 583-40-4
Molecular Formula C5H4N4S
Molecular Weight 152.02 g/mol
LogP 1.01549
Topological Polar Surface Area 57.36 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 0
Exact Mass 152.01567
Heavy Atoms 10
Complexity 364.9402

Chemical Identifiers

CAS Number 583-40-4
SMILES C1=C2C(=NC=N1)NC(=S)N2

Product Overview

7H-Purine-8-thiol (CAS 583-40-4), with molecular formula C5H4N4S and molecular weight 152.02 g/mol. IUPAC: 7,9-dihydropurine-8-thione.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 7H-Purine-8-thiol

XLogP
1.01549
TPSA (Topological Polar Surface Area)
57.36
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
0
Heavy Atoms
10
Complexity
364.9402
Exact Mass
152.01567
Monoisotopic Mass
152.01567
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 7H-Purine-8-thiol

The XLogP value of 1.01549 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 7H-Purine-8-thiol. With a topological polar surface area (TPSA) of 57.36 Ų, 7H-Purine-8-thiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 7H-Purine-8-thiol has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 7H-Purine-8-thiol?

The CAS number of 7H-Purine-8-thiol is 583-40-4.

What is the molecular formula of 7H-Purine-8-thiol?

The molecular formula of 7H-Purine-8-thiol is C5H4N4S.

What is the molecular weight of 7H-Purine-8-thiol?

The molecular weight of 7H-Purine-8-thiol is 152.02 g/mol.

Where can I buy 7H-Purine-8-thiol?

You can request a quote for 7H-Purine-8-thiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 7H-Purine-8-thiol?

Yes, KEHONG BIO provides custom synthesis services for 7H-Purine-8-thiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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