Nsc 246132 structure

Nsc 246132

TL;DR: Nsc 246132 (CAS 58161-65-2) is a chemical compound with molecular formula C33H40ClN3O12 and molecular weight 705.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-2-[[2-(dimethylamino)acetyl]amino]acetamide;hydrochloride

Also Known As: Nsc 246132, 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-((2,3,6-trideoxy-3-((N-(N,N-dimethylglycyl)glycyl)amino)-alpha-L-lyxo-hexopyranosyl)oxy)-, monohydrochloride, (8S-cis)-, 8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-((2,3,6-trideoxy-3-((N-(N,N-dimethylglycyl)glycyl)amino)-alpha-L-lyxo-hexopyranosyl)oxy)-5,12-naphthacenedione monohydrochloride, (8S-cis)-, 5,12-NAPHTHACENEDIONE, 8-ACETYL-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-1-METHOXY-10-((2,3,6-TRIDEOXY-3-((N-(N,N-DIMETHYLGLYCYL)GLYCYL)AMINO)-.ALPHA.-L-LYXO-HEXOPYRANOSYL)OXY)-, MONOHYDROCHLORIDE, (8S-CIS)-, 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[(dimethylamino)acetyl]amino]acetyl]amino]-.alpha.-L-lyxo-hexopyranosyl]oxy]-, monohydrochloride, (8S-cis)-

CAS: 58161-65-2
Molecular Formula C33H40ClN3O12
Molecular Weight 705.23 g/mol
LogP 0.286
Topological Polar Surface Area 221.0 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 13
Rotatable Bonds 9
Exact Mass 705.23004
Heavy Atoms 49
Complexity 1260.0

Chemical Identifiers

CAS Number 58161-65-2
SMILES C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)NC(=O)CNC(=O)CN(C)C)O.Cl
InChIKey ZVPGKONLVQAMJZ-SGLHZKEVSA-N

Product Overview

Nsc 246132 (CAS 58161-65-2), with molecular formula C33H40ClN3O12 and molecular weight 705.23 g/mol. IUPAC: N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-2-[[2-(dimethylamino)acetyl]amino]acetamide;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Nsc 246132

XLogP
0.286
TPSA (Topological Polar Surface Area)
221.0
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
13
Rotatable Bonds
9
Heavy Atoms
49
Complexity
1260.0
Exact Mass
705.23004
Monoisotopic Mass
705.23004
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Nsc 246132

The XLogP value of 0.286 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nsc 246132. The TPSA of 221.0 Ų indicates high polarity, suggesting Nsc 246132 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Nsc 246132 has 7 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Nsc 246132?

The CAS number of Nsc 246132 is 58161-65-2.

What is the molecular formula of Nsc 246132?

The molecular formula of Nsc 246132 is C33H40ClN3O12.

What is the molecular weight of Nsc 246132?

The molecular weight of Nsc 246132 is 705.23 g/mol.

Where can I buy Nsc 246132?

You can request a quote for Nsc 246132 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Nsc 246132?

Yes, KEHONG BIO provides custom synthesis services for Nsc 246132 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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