1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione
TL;DR: 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione (CAS 5809-69-8) is a chemical compound with molecular formula C18H22N2OS and molecular weight 314.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(3-hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione
Also Known As: F0332-0048, AF-399/13041028, 1-(3-hydroxypropyl)-2-(p-tolyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione, 1-(3-hydroxypropyl)-2-(4-methylphenyl)-1,4,5,6,7,8-hexahydroquinazoline-4-thione, 1-(3-hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydro-4(1H)-quinazolinethione
| Molecular Formula | C18H22N2OS |
|---|---|
| Molecular Weight | 314.15 g/mol |
| LogP | 3.84921 |
| Topological Polar Surface Area | 38.05 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 314.1453 |
| Heavy Atoms | 22 |
| Complexity | 719.1024 |
Chemical Identifiers
| CAS Number | 5809-69-8 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=NC(=S)C3=C(N2CCCO)CCCC3 |
Product Overview
1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione (CAS 5809-69-8), with molecular formula C18H22N2OS and molecular weight 314.15 g/mol. IUPAC: 1-(3-hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione.
Chemical Property Profile of 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione
Property Insights of 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione
The XLogP value of 3.84921 indicates that 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.05 Ų, 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione?
The CAS number of 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione is 5809-69-8.
What is the molecular formula of 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione?
The molecular formula of 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione is C18H22N2OS.
What is the molecular weight of 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione?
The molecular weight of 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione is 314.15 g/mol.
Where can I buy 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione?
You can request a quote for 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione?
Yes, KEHONG BIO provides custom synthesis services for 1-(3-Hydroxypropyl)-2-(4-methylphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.