Desipramine Hydrochloride
TL;DR: Desipramine Hydrochloride (CAS 58-28-6) is a chemical compound with molecular formula C18H23ClN2 and molecular weight 302.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine;hydrochloride
Also Known As: Desipramine hydrochloride, Desipramine Hcl, Norpramin, Pertofrane, Pertofran
| Molecular Formula | C18H23ClN2 |
|---|---|
| Molecular Weight | 302.15 g/mol |
| LogP | 3.95 |
| Topological Polar Surface Area | 15.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 302.15497 |
| Heavy Atoms | 21 |
| Complexity | 267.0 |
| Solubility | >45.4 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 58-28-6 |
|---|---|
| SMILES | CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl |
| InChIKey | XAEWZDYWZHIUCT-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Desipramine Hydrochloride (CAS 58-28-6), with molecular formula C18H23ClN2 and molecular weight 302.15 g/mol. IUPAC: 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine;hydrochloride.
Chemical Property Profile of Desipramine Hydrochloride
Property Insights of Desipramine Hydrochloride
The XLogP value of 3.95 indicates that Desipramine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.3 Ų, Desipramine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Desipramine Hydrochloride has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Desipramine Hydrochloride?
The CAS number of Desipramine Hydrochloride is 58-28-6.
What is the molecular formula of Desipramine Hydrochloride?
The molecular formula of Desipramine Hydrochloride is C18H23ClN2.
What is the molecular weight of Desipramine Hydrochloride?
The molecular weight of Desipramine Hydrochloride is 302.15 g/mol.
Where can I buy Desipramine Hydrochloride?
You can request a quote for Desipramine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Desipramine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Desipramine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.