Losalen
TL;DR: Losalen (CAS 57973-63-4) is a chemical compound with molecular formula C34H42F2O9 and molecular weight 632.28 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[2-[(6S,8S,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate;2-hydroxybenzoic acid
Also Known As: Losalen, Locasalen, Flumethasone pivalate mixture with salicylic acid, [2-[(6S,8S,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate;2-hydroxybenzoic acid, 2-Hydroxybenzoic acid--6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl 2,2-dimethylpropanoate (1/1)
| Molecular Formula | C34H42F2O9 |
|---|---|
| Molecular Weight | 632.28 g/mol |
| LogP | 4.5311 |
| Topological Polar Surface Area | 158.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 6 |
| Exact Mass | 632.27966 |
| Heavy Atoms | 45 |
| Complexity | 1160.0 |
Chemical Identifiers
| CAS Number | 57973-63-4 |
|---|---|
| SMILES | C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4(C3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C(C)(C)C)O)C)O)F)C)F.C1=CC=C(C(=C1)C(=O)O)O |
| InChIKey | KSTPLQAJWSYHTP-SAPBVRDASA-N |
Product Overview
Losalen (CAS 57973-63-4), with molecular formula C34H42F2O9 and molecular weight 632.28 g/mol. IUPAC: [2-[(6S,8S,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate;2-hydroxybenzoic acid.
Chemical Property Profile of Losalen
Property Insights of Losalen
The XLogP value of 4.5311 indicates that Losalen is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 158.0 Ų indicates high polarity, suggesting Losalen may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Losalen has 4 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Losalen?
The CAS number of Losalen is 57973-63-4.
What is the molecular formula of Losalen?
The molecular formula of Losalen is C34H42F2O9.
What is the molecular weight of Losalen?
The molecular weight of Losalen is 632.28 g/mol.
Where can I buy Losalen?
You can request a quote for Losalen directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Losalen?
Yes, KEHONG BIO provides custom synthesis services for Losalen and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.