Clazepam
TL;DR: Clazepam (CAS 57916-70-8) is a chemical compound with molecular formula C21H21ClN2O2 and molecular weight 368.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-3H-1,4-benzodiazepin-2-one
Also Known As: Iclazepam, Iclazepamum, Clazepam, Iclazepam [INN], Iclazepamum [INN-Latin]
| Molecular Formula | C21H21ClN2O2 |
|---|---|
| Molecular Weight | 368.13 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 41.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 6 |
| Exact Mass | 368.12915 |
| Heavy Atoms | 26 |
| Complexity | 528.0 |
Chemical Identifiers
| CAS Number | 57916-70-8 |
|---|---|
| SMILES | C1CC1COCCN2C(=O)CN=C(C3=C2C=CC(=C3)Cl)C4=CC=CC=C4 |
| InChIKey | PLRHQQPBNXIHAZ-UHFFFAOYSA-N |
Product Overview
Clazepam (CAS 57916-70-8), with molecular formula C21H21ClN2O2 and molecular weight 368.13 g/mol. IUPAC: 7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-3H-1,4-benzodiazepin-2-one.
Chemical Property Profile of Clazepam
Property Insights of Clazepam
The XLogP value of 3.4 indicates that Clazepam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.9 Ų, Clazepam exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Clazepam has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Clazepam?
The CAS number of Clazepam is 57916-70-8.
What is the molecular formula of Clazepam?
The molecular formula of Clazepam is C21H21ClN2O2.
What is the molecular weight of Clazepam?
The molecular weight of Clazepam is 368.13 g/mol.
Where can I buy Clazepam?
You can request a quote for Clazepam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Clazepam?
Yes, KEHONG BIO provides custom synthesis services for Clazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.