![(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione structure](/static/products/578/578760-98-2.png)
(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione
TL;DR: (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione (CAS 578760-98-2) is a chemical compound with molecular formula C23H20N2O5S and molecular weight 436.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy-(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione
Also Known As: (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione, (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy-(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione, 1-(4,5-dimethyl(1,3-thiazol-2-yl))-3-hydroxy-5-(3-hydroxyphenyl)-4-[(4-methoxy phenyl)carbonyl]-3-pyrrolin-2-one, 1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-5-(3-hydroxyphenyl)-4-(4-methoxybenzoyl)-1H-pyrrol-2(5H)-one
| Molecular Formula | C23H20N2O5S |
|---|---|
| Molecular Weight | 436.11 g/mol |
| LogP | 4.10044 |
| Topological Polar Surface Area | 99.96 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 436.10928 |
| Heavy Atoms | 31 |
| Complexity | 1193.4597 |
Chemical Identifiers
| CAS Number | 578760-98-2 |
|---|---|
| SMILES | CC1=C(SC(=N1)N2C(/C(=C(/C3=CC=C(C=C3)OC)\O)/C(=O)C2=O)C4=CC(=CC=C4)O)C |
Product Overview
(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione (CAS 578760-98-2), with molecular formula C23H20N2O5S and molecular weight 436.11 g/mol. IUPAC: (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy-(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione.
Chemical Property Profile of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione
Property Insights of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione
The XLogP value of 4.10044 indicates that (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 99.96 Ų falls within the moderate polarity range, balancing permeability and solubility for (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione. Following Lipinski's Rule of Five, (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione?
The CAS number of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione is 578760-98-2.
What is the molecular formula of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione?
The molecular formula of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione is C23H20N2O5S.
What is the molecular weight of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione?
The molecular weight of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione is 436.11 g/mol.
Where can I buy (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione?
You can request a quote for (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methoxyphenyl)methylidene]-5-(3-hydroxyphenyl)pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.