(Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one
TL;DR: (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one (CAS 578749-66-3) is a chemical compound with molecular formula C19H16Cl2N2O2S and molecular weight 406.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[[5-(2,4-dichlorophenyl)furan-2-yl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one
Also Known As: (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one, (5Z)-5-[[5-(2,4-dichlorophenyl)furan-2-yl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one, (5Z)-5-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-(piperidin-1-yl)-1,3-thiazol-4(5H)-one
| Molecular Formula | C19H16Cl2N2O2S |
|---|---|
| Molecular Weight | 406.03 g/mol |
| LogP | 5.7096 |
| Topological Polar Surface Area | 45.81 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 406.03094 |
| Heavy Atoms | 26 |
| Complexity | 914.013 |
Chemical Identifiers
| CAS Number | 578749-66-3 |
|---|---|
| SMILES | C1CCN(CC1)C2=NC(=O)/C(=C/C3=CC=C(O3)C4=C(C=C(C=C4)Cl)Cl)/S2 |
Product Overview
(Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one (CAS 578749-66-3), with molecular formula C19H16Cl2N2O2S and molecular weight 406.03 g/mol. IUPAC: (5Z)-5-[[5-(2,4-dichlorophenyl)furan-2-yl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one.
Chemical Property Profile of (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one
Property Insights of (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one
The XLogP value of 5.7096 indicates that (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.81 Ų, (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one?
The CAS number of (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one is 578749-66-3.
What is the molecular formula of (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one?
The molecular formula of (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one is C19H16Cl2N2O2S.
What is the molecular weight of (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one?
The molecular weight of (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one is 406.03 g/mol.
Where can I buy (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one?
You can request a quote for (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-(piperidin-1-yl)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.