(E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide
TL;DR: (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide (CAS 578748-93-3) is a chemical compound with molecular formula C22H16FN3O4S and molecular weight 437.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2-fluorophenyl)-2-[(5E)-5-[[1-(4-hydroxyphenyl)pyrrol-2-yl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide
Also Known As: (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide, N-(2-fluorophenyl)-2-[(5E)-5-[[1-(4-hydroxyphenyl)pyrrol-2-yl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide
| Molecular Formula | C22H16FN3O4S |
|---|---|
| Molecular Weight | 437.08 g/mol |
| LogP | 3.997 |
| Topological Polar Surface Area | 91.64 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 437.08456 |
| Heavy Atoms | 31 |
| Complexity | 1203.4749 |
Chemical Identifiers
| CAS Number | 578748-93-3 |
|---|---|
| SMILES | C1=CC=C(C(=C1)NC(=O)CN2C(=O)/C(=C\C3=CC=CN3C4=CC=C(C=C4)O)/SC2=O)F |
Product Overview
(E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide (CAS 578748-93-3), with molecular formula C22H16FN3O4S and molecular weight 437.08 g/mol. IUPAC: N-(2-fluorophenyl)-2-[(5E)-5-[[1-(4-hydroxyphenyl)pyrrol-2-yl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide.
Chemical Property Profile of (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide
Property Insights of (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide
The XLogP value of 3.997 indicates that (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 91.64 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide. Following Lipinski's Rule of Five, (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide?
The CAS number of (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide is 578748-93-3.
What is the molecular formula of (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide?
The molecular formula of (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide is C22H16FN3O4S.
What is the molecular weight of (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide?
The molecular weight of (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide is 437.08 g/mol.
Where can I buy (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide?
You can request a quote for (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(2-fluorophenyl)-2-(5-((1-(4-hydroxyphenyl)-1H-pyrrol-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.