(Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one
TL;DR: (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one (CAS 578745-40-1) is a chemical compound with molecular formula C24H16N4O4 and molecular weight 424.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(Z)-(1-methyl-2-oxoindol-3-ylidene)methyl]-3-(4-nitrophenyl)quinazolin-4-one
Also Known As: (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one, 2-[(1-methyl-2-oxo-indol-3-ylidene)methyl]-3-(4-nitrophenyl)quinazolin-4-one, 2-[(Z)-(1-methyl-2-oxoindol-3-ylidene)methyl]-3-(4-nitrophenyl)quinazolin-4-one, 2-[(Z)-(1-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-3-(4-nitrophenyl)quinazolin-4(3H)-one
| Molecular Formula | C24H16N4O4 |
|---|---|
| Molecular Weight | 424.12 g/mol |
| LogP | 3.8109 |
| Topological Polar Surface Area | 98.34 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 424.11716 |
| Heavy Atoms | 32 |
| Complexity | 1502.9708 |
Chemical Identifiers
| CAS Number | 578745-40-1 |
|---|---|
| SMILES | CN1C2=CC=CC=C2/C(=C/C3=NC4=CC=CC=C4C(=O)N3C5=CC=C(C=C5)[N+](=O)[O-])/C1=O |
Product Overview
(Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one (CAS 578745-40-1), with molecular formula C24H16N4O4 and molecular weight 424.12 g/mol. IUPAC: 2-[(Z)-(1-methyl-2-oxoindol-3-ylidene)methyl]-3-(4-nitrophenyl)quinazolin-4-one.
Chemical Property Profile of (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one
Property Insights of (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one
The XLogP value of 3.8109 indicates that (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 98.34 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one. Following Lipinski's Rule of Five, (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one?
The CAS number of (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one is 578745-40-1.
What is the molecular formula of (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one?
The molecular formula of (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one is C24H16N4O4.
What is the molecular weight of (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one?
The molecular weight of (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one is 424.12 g/mol.
Where can I buy (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one?
You can request a quote for (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-2-((1-methyl-2-oxoindolin-3-ylidene)methyl)-3-(4-nitrophenyl)quinazolin-4(3H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.