BAS 12457933 structure

BAS 12457933

TL;DR: BAS 12457933 (CAS 578720-52-2) is a chemical compound with molecular formula C22H28N6OS and molecular weight 424.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[13-(4-methylpiperazin-1-yl)-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1,7,9,12,14,16-hexaen-8-yl]morpholine

Also Known As: BAS 12457933, 4-(8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine, 8-(4-methylpiperazin-1-yl)-5-(morpholin-4-yl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinoline

CAS: 578720-52-2
Molecular Formula C22H28N6OS
Molecular Weight 424.20 g/mol
LogP 2.7067
Topological Polar Surface Area 57.62 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 8
Rotatable Bonds 2
Exact Mass 424.20453
Heavy Atoms 30
Complexity 1084.3516

Chemical Identifiers

CAS Number 578720-52-2
SMILES CN1CCN(CC1)C2=NC=NC3=C2SC4=C3C5=C(CCCC5)C(=N4)N6CCOCC6

Product Overview

BAS 12457933 (CAS 578720-52-2), with molecular formula C22H28N6OS and molecular weight 424.20 g/mol. IUPAC: 4-[13-(4-methylpiperazin-1-yl)-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1,7,9,12,14,16-hexaen-8-yl]morpholine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of BAS 12457933

XLogP
2.7067
TPSA (Topological Polar Surface Area)
57.62
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
8
Rotatable Bonds
2
Heavy Atoms
30
Complexity
1084.3516
Exact Mass
424.20453
Monoisotopic Mass
424.20453
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of BAS 12457933

The XLogP value of 2.7067 suggests moderate lipophilicity, balancing water solubility and membrane permeability for BAS 12457933. With a topological polar surface area (TPSA) of 57.62 Ų, BAS 12457933 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, BAS 12457933 has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of BAS 12457933?

The CAS number of BAS 12457933 is 578720-52-2.

What is the molecular formula of BAS 12457933?

The molecular formula of BAS 12457933 is C22H28N6OS.

What is the molecular weight of BAS 12457933?

The molecular weight of BAS 12457933 is 424.20 g/mol.

Where can I buy BAS 12457933?

You can request a quote for BAS 12457933 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for BAS 12457933?

Yes, KEHONG BIO provides custom synthesis services for BAS 12457933 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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