![1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one structure](/static/products/5785/5785-27-3.webp)
1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one
TL;DR: 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one (CAS 5785-27-3) is a chemical compound with molecular formula C20H19F3N2O2 and molecular weight 376.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-[4-(2,3-difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl]ethanone
Also Known As: 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one, AB00096685-01, 1-[4-[4-(2,3-difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl]ethanone, 1-{4-[4-(2,3-difluorobenzoyl)-1-piperazinyl]-5-fluoro-2-methylphenyl}ethanone
| Molecular Formula | C20H19F3N2O2 |
|---|---|
| Molecular Weight | 376.14 g/mol |
| LogP | 3.57732 |
| Topological Polar Surface Area | 40.62 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 376.13986 |
| Heavy Atoms | 27 |
| Complexity | 906.3401 |
Chemical Identifiers
| CAS Number | 5785-27-3 |
|---|---|
| SMILES | CC1=CC(=C(C=C1C(=O)C)F)N2CCN(CC2)C(=O)C3=C(C(=CC=C3)F)F |
Product Overview
1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one (CAS 5785-27-3), with molecular formula C20H19F3N2O2 and molecular weight 376.14 g/mol. IUPAC: 1-[4-[4-(2,3-difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl]ethanone.
Chemical Property Profile of 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one
Property Insights of 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one
The XLogP value of 3.57732 indicates that 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.62 Ų, 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one?
The CAS number of 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one is 5785-27-3.
What is the molecular formula of 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one?
The molecular formula of 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one is C20H19F3N2O2.
What is the molecular weight of 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one?
The molecular weight of 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one is 376.14 g/mol.
Where can I buy 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one?
You can request a quote for 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one?
Yes, KEHONG BIO provides custom synthesis services for 1-{4-[4-(2,3-Difluorobenzoyl)piperazin-1-yl]-5-fluoro-2-methylphenyl}ethan-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.