Cefedrolor structure

Cefedrolor

TL;DR: Cefedrolor (CAS 57848-28-9) is a chemical compound with molecular formula C16H16ClN3O5S and molecular weight 397.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(6R,7R)-7-[[(2R)-2-amino-2-(3-chloro-4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Also Known As: Cefedrolor, Cefedrolor [INN], cefedrolorum, BMY 25154, KST-1A7038

CAS: 57848-28-9
Molecular Formula C16H16ClN3O5S
Molecular Weight 397.05 g/mol
LogP -1.4
Topological Polar Surface Area 158.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 7
Rotatable Bonds 4
Exact Mass 397.04993
Heavy Atoms 26
Complexity 672.0

Chemical Identifiers

CAS Number 57848-28-9
SMILES CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC(=C(C=C3)O)Cl)N)SC1)C(=O)O
InChIKey RULITNAIJFZYLO-UEKVPHQBSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (6 patents) Pharmaceutical Intermediates (13 patents)

Product Overview

Cefedrolor (CAS 57848-28-9), with molecular formula C16H16ClN3O5S and molecular weight 397.05 g/mol. IUPAC: (6R,7R)-7-[[(2R)-2-amino-2-(3-chloro-4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Cefedrolor

XLogP
-1.4
TPSA (Topological Polar Surface Area)
158.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
7
Rotatable Bonds
4
Heavy Atoms
26
Complexity
672.0
Exact Mass
397.04993
Monoisotopic Mass
397.04993
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Cefedrolor

The XLogP value of -1.4 indicates that Cefedrolor is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 158.0 Ų indicates high polarity, suggesting Cefedrolor may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Cefedrolor has 4 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Cefedrolor?

The CAS number of Cefedrolor is 57848-28-9.

What is the molecular formula of Cefedrolor?

The molecular formula of Cefedrolor is C16H16ClN3O5S.

What is the molecular weight of Cefedrolor?

The molecular weight of Cefedrolor is 397.05 g/mol.

Where can I buy Cefedrolor?

You can request a quote for Cefedrolor directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Cefedrolor?

Yes, KEHONG BIO provides custom synthesis services for Cefedrolor and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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