2-Chloro-N-(4-fluorophenyl)nicotinamide
TL;DR: 2-Chloro-N-(4-fluorophenyl)nicotinamide (CAS 57841-99-3) is a chemical compound with molecular formula C12H8ClFN2O and molecular weight 250.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-N-(4-fluorophenyl)pyridine-3-carboxamide
Also Known As: 2-CHLORO-N-(4-FLUOROPHENYL)NICOTINAMIDE, 2-chloro-N-(4-fluorophenyl)pyridine-3-carboxamide, 2-chloro-N-(4-fluoro-phenyl)-nicotinamide, J2.356.779B, 2-Chloro-N-(4-fluorophenyl)-pyridine-3-carboxamide
| Molecular Formula | C12H8ClFN2O |
|---|---|
| Molecular Weight | 250.03 g/mol |
| LogP | 3.1264 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 250.03091 |
| Heavy Atoms | 17 |
| Complexity | 542.45685 |
Chemical Identifiers
| CAS Number | 57841-99-3 |
|---|---|
| SMILES | C1=CC(=C(N=C1)Cl)C(=O)NC2=CC=C(C=C2)F |
Product Overview
2-Chloro-N-(4-fluorophenyl)nicotinamide (CAS 57841-99-3), with molecular formula C12H8ClFN2O and molecular weight 250.03 g/mol. IUPAC: 2-chloro-N-(4-fluorophenyl)pyridine-3-carboxamide.
Chemical Property Profile of 2-Chloro-N-(4-fluorophenyl)nicotinamide
Property Insights of 2-Chloro-N-(4-fluorophenyl)nicotinamide
The XLogP value of 3.1264 indicates that 2-Chloro-N-(4-fluorophenyl)nicotinamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 2-Chloro-N-(4-fluorophenyl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-N-(4-fluorophenyl)nicotinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-N-(4-fluorophenyl)nicotinamide?
The CAS number of 2-Chloro-N-(4-fluorophenyl)nicotinamide is 57841-99-3.
What is the molecular formula of 2-Chloro-N-(4-fluorophenyl)nicotinamide?
The molecular formula of 2-Chloro-N-(4-fluorophenyl)nicotinamide is C12H8ClFN2O.
What is the molecular weight of 2-Chloro-N-(4-fluorophenyl)nicotinamide?
The molecular weight of 2-Chloro-N-(4-fluorophenyl)nicotinamide is 250.03 g/mol.
Where can I buy 2-Chloro-N-(4-fluorophenyl)nicotinamide?
You can request a quote for 2-Chloro-N-(4-fluorophenyl)nicotinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-N-(4-fluorophenyl)nicotinamide?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-N-(4-fluorophenyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.