![(E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one structure](/static/products/578/578002-34-3.png)
(E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one
TL;DR: (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one (CAS 578002-34-3) is a chemical compound with molecular formula C25H20N2O3 and molecular weight 396.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-3-(2,4-dimethylphenyl)quinazolin-4-one
Also Known As: (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one, 2-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one, 2-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-3-(2,4-dimethylphenyl)quinazolin-4-one
| Molecular Formula | C25H20N2O3 |
|---|---|
| Molecular Weight | 396.15 g/mol |
| LogP | 4.90164 |
| Topological Polar Surface Area | 53.35 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 396.1474 |
| Heavy Atoms | 30 |
| Complexity | 1368.9326 |
Chemical Identifiers
| CAS Number | 578002-34-3 |
|---|---|
| SMILES | CC1=CC(=C(C=C1)N2C(=NC3=CC=CC=C3C2=O)/C=C/C4=CC5=C(C=C4)OCO5)C |
Product Overview
(E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one (CAS 578002-34-3), with molecular formula C25H20N2O3 and molecular weight 396.15 g/mol. IUPAC: 2-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-3-(2,4-dimethylphenyl)quinazolin-4-one.
Chemical Property Profile of (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one
Property Insights of (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one
The XLogP value of 4.90164 indicates that (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.35 Ų, (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one?
The CAS number of (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one is 578002-34-3.
What is the molecular formula of (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one?
The molecular formula of (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one is C25H20N2O3.
What is the molecular weight of (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one?
The molecular weight of (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one is 396.15 g/mol.
Where can I buy (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one?
You can request a quote for (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-3-(2,4-dimethylphenyl)quinazolin-4(3H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.