N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine
TL;DR: N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine (CAS 577989-72-1) is a chemical compound with molecular formula C22H28N4 and molecular weight 348.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(1-adamantyl)-2-pyrrolidin-1-ylquinazolin-4-amine
Also Known As: AB01300639-01, AB01300639-04, N-(1-adamantyl)-2-pyrrolidin-1-ylquinazolin-4-amine, N-(ADAMANTAN-1-YL)-2-(PYRROLIDIN-1-YL)QUINAZOLIN-4-AMINE, N-((3s,5s,7s)-adamantan-1-yl)-2-(pyrrolidin-1-yl)quinazolin-4-amine
| Molecular Formula | C22H28N4 |
|---|---|
| Molecular Weight | 348.23 g/mol |
| LogP | 4.6107 |
| Topological Polar Surface Area | 41.05 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 348.23138 |
| Heavy Atoms | 26 |
| Complexity | 803.86694 |
Chemical Identifiers
| CAS Number | 577989-72-1 |
|---|---|
| SMILES | C1CCN(C1)C2=NC3=CC=CC=C3C(=N2)NC45CC6CC(C4)CC(C6)C5 |
Product Overview
N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine (CAS 577989-72-1), with molecular formula C22H28N4 and molecular weight 348.23 g/mol. IUPAC: N-(1-adamantyl)-2-pyrrolidin-1-ylquinazolin-4-amine.
Chemical Property Profile of N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine
Property Insights of N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine
The XLogP value of 4.6107 indicates that N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.05 Ų, N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine?
The CAS number of N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine is 577989-72-1.
What is the molecular formula of N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine?
The molecular formula of N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine is C22H28N4.
What is the molecular weight of N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine?
The molecular weight of N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine is 348.23 g/mol.
Where can I buy N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine?
You can request a quote for N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine?
Yes, KEHONG BIO provides custom synthesis services for N-(Adamantan-1-YL)-2-(pyrrolidin-1-YL)quinazolin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.