A3757/0159328 structure

A3757/0159328

TL;DR: A3757/0159328 (CAS 577987-46-3) is a chemical compound with molecular formula C17H20FN3O2S and molecular weight 349.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(4-fluorophenyl)-1-pentan-2-yl-4,8-dihydro-2H-pyrazolo[3,4-e][1,4]thiazepine-3,7-dione

Also Known As: A3757/0159328, 4-(4-fluorophenyl)-1-pentan-2-yl-4,8-dihydro-2H-pyrazolo[3,4-e][1,4]thiazepine-3,7-dione, 4-(4-FLUOROPHENYL)-3-HYDROXY-1-(PENTAN-2-YL)-1H,4H,6H,7H,8H-PYRAZOLO[3,4-E][1,4]THIAZEPIN-7-ONE, 4-(4-fluorophenyl)-3-hydroxy-1-(pentan-2-yl)-4,8-dihydro-1H-pyrazolo[3,4-e][1,4]thiazepin-7(6H)-one, 4-(4-fluorophenyl)-3-hydroxy-1-(pentan-2-yl)-6,8-dihydro-1H-pyrazolo[3,4-e][1,4]thiazepin-7(4H)-one

CAS: 577987-46-3
Molecular Formula C17H20FN3O2S
Molecular Weight 349.13 g/mol
LogP 3.4513
Topological Polar Surface Area 66.89 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 349.12604
Heavy Atoms 24
Complexity 797.1572

Chemical Identifiers

CAS Number 577987-46-3
SMILES CCCC(C)N1C2=C(C(SCC(=O)N2)C3=CC=C(C=C3)F)C(=O)N1

Product Overview

A3757/0159328 (CAS 577987-46-3), with molecular formula C17H20FN3O2S and molecular weight 349.13 g/mol. IUPAC: 4-(4-fluorophenyl)-1-pentan-2-yl-4,8-dihydro-2H-pyrazolo[3,4-e][1,4]thiazepine-3,7-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of A3757/0159328

XLogP
3.4513
TPSA (Topological Polar Surface Area)
66.89
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
24
Complexity
797.1572
Exact Mass
349.12604
Monoisotopic Mass
349.12604
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of A3757/0159328

The XLogP value of 3.4513 indicates that A3757/0159328 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.89 Ų falls within the moderate polarity range, balancing permeability and solubility for A3757/0159328. Following Lipinski's Rule of Five, A3757/0159328 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of A3757/0159328?

The CAS number of A3757/0159328 is 577987-46-3.

What is the molecular formula of A3757/0159328?

The molecular formula of A3757/0159328 is C17H20FN3O2S.

What is the molecular weight of A3757/0159328?

The molecular weight of A3757/0159328 is 349.13 g/mol.

Where can I buy A3757/0159328?

You can request a quote for A3757/0159328 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for A3757/0159328?

Yes, KEHONG BIO provides custom synthesis services for A3757/0159328 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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