N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide structure

N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide

TL;DR: N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide (CAS 577981-90-9) is a chemical compound with molecular formula C22H24N2O2 and molecular weight 348.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-methyl-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-methylphenyl)propanamide

Also Known As: N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide, 2-methyl-N-[(8-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]-N-(2-methylphenyl)propanamide, 2-methyl-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-methylphenyl)propanamide

CAS: 577981-90-9
Molecular Formula C22H24N2O2
Molecular Weight 348.18 g/mol
LogP 4.33414
Topological Polar Surface Area 53.17 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 4
Exact Mass 348.18378
Heavy Atoms 26
Complexity 1018.07117

Chemical Identifiers

CAS Number 577981-90-9
SMILES CC1=C2C(=CC=C1)C=C(C(=O)N2)CN(C3=CC=CC=C3C)C(=O)C(C)C

Product Overview

N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide (CAS 577981-90-9), with molecular formula C22H24N2O2 and molecular weight 348.18 g/mol. IUPAC: 2-methyl-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-methylphenyl)propanamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide

XLogP
4.33414
TPSA (Topological Polar Surface Area)
53.17
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
4
Heavy Atoms
26
Complexity
1018.07117
Exact Mass
348.18378
Monoisotopic Mass
348.18378
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide

The XLogP value of 4.33414 indicates that N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.17 Ų, N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide?

The CAS number of N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide is 577981-90-9.

What is the molecular formula of N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide?

The molecular formula of N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide is C22H24N2O2.

What is the molecular weight of N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide?

The molecular weight of N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide is 348.18 g/mol.

Where can I buy N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide?

You can request a quote for N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide?

Yes, KEHONG BIO provides custom synthesis services for N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(o-tolyl)isobutyramide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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