4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one
TL;DR: 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one (CAS 577962-73-3) is a chemical compound with molecular formula C20H15ClN2O3S2 and molecular weight 430.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[(4-chlorophenyl)-hydroxymethylidene]-1-(4,5-dimethyl-1,3-thiazol-2-yl)-5-thiophen-2-ylpyrrolidine-2,3-dione
Also Known As: 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one, 4-[(4-chlorophenyl)-hydroxymethylidene]-1-(4,5-dimethyl-1,3-thiazol-2-yl)-5-thiophen-2-ylpyrrolidine-2,3-dione
| Molecular Formula | C20H15ClN2O3S2 |
|---|---|
| Molecular Weight | 430.02 g/mol |
| LogP | 5.10114 |
| Topological Polar Surface Area | 70.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 430.02127 |
| Heavy Atoms | 28 |
| Complexity | 1081.6866 |
Chemical Identifiers
| CAS Number | 577962-73-3 |
|---|---|
| SMILES | CC1=C(SC(=N1)N2C(C(=C(C3=CC=C(C=C3)Cl)O)C(=O)C2=O)C4=CC=CS4)C |
Product Overview
4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one (CAS 577962-73-3), with molecular formula C20H15ClN2O3S2 and molecular weight 430.02 g/mol. IUPAC: 4-[(4-chlorophenyl)-hydroxymethylidene]-1-(4,5-dimethyl-1,3-thiazol-2-yl)-5-thiophen-2-ylpyrrolidine-2,3-dione.
Chemical Property Profile of 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one
Property Insights of 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one
The XLogP value of 5.10114 indicates that 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one. Following Lipinski's Rule of Five, 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
The CAS number of 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one is 577962-73-3.
What is the molecular formula of 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
The molecular formula of 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one is C20H15ClN2O3S2.
What is the molecular weight of 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
The molecular weight of 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one is 430.02 g/mol.
Where can I buy 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
You can request a quote for 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-chlorobenzoyl)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-3-hydroxy-5-(thiophen-2-yl)-2,5-dihydro-1H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.