![(5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione structure](/static/products/577/577789-52-7.png)
(5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione
TL;DR: (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione (CAS 577789-52-7) is a chemical compound with molecular formula C25H27N3O5 and molecular weight 449.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(1-butyl-2,3-dihydroindol-5-yl)methylidene]-1-(2,5-dimethoxyphenyl)-1,3-diazinane-2,4,6-trione
Also Known As: (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione, (5E)-5-[(1-butyl-2,3-dihydroindol-5-yl)methylidene]-1-(2,5-dimethoxyphenyl)-1,3-diazinane-2,4,6-trione, (E)-5-((1-butylindolin-5-yl)methylene)-1-(2,5-dimethoxyphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione, 5-[(1-butyl-2,3-dihydroindol-5-yl)methylidene]-1-(2,5-dimethoxyphenyl)-1,3-diazinane-2,4,6-trione
| Molecular Formula | C25H27N3O5 |
|---|---|
| Molecular Weight | 449.20 g/mol |
| LogP | 3.5328 |
| Topological Polar Surface Area | 88.18 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 449.19507 |
| Heavy Atoms | 33 |
| Complexity | 1140.8574 |
Chemical Identifiers
| CAS Number | 577789-52-7 |
|---|---|
| SMILES | CCCCN1CCC2=C1C=CC(=C2)/C=C/3\C(=O)NC(=O)N(C3=O)C4=C(C=CC(=C4)OC)OC |
Product Overview
(5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione (CAS 577789-52-7), with molecular formula C25H27N3O5 and molecular weight 449.20 g/mol. IUPAC: (5E)-5-[(1-butyl-2,3-dihydroindol-5-yl)methylidene]-1-(2,5-dimethoxyphenyl)-1,3-diazinane-2,4,6-trione.
Chemical Property Profile of (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione
Property Insights of (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione
The XLogP value of 3.5328 indicates that (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.18 Ų falls within the moderate polarity range, balancing permeability and solubility for (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione. Following Lipinski's Rule of Five, (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione?
The CAS number of (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione is 577789-52-7.
What is the molecular formula of (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione?
The molecular formula of (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione is C25H27N3O5.
What is the molecular weight of (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione?
The molecular weight of (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione is 449.20 g/mol.
Where can I buy (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione?
You can request a quote for (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione?
Yes, KEHONG BIO provides custom synthesis services for (5E)-5-[(1-butyl-2,3-dihydro-1H-indol-5-yl)methylidene]-3-(2,5-dimethoxyphenyl)-6-hydroxypyrimidine-2,4(3H,5H)-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.