![N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine structure](/static/products/5777/577787-40-7.webp)
N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine
TL;DR: N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine (CAS 577787-40-7) is a chemical compound with molecular formula C22H24N4O4S2 and molecular weight 472.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(Z)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine
Also Known As: N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine, 2-[(2Z)-2-(2,3-dimethoxybenzylidene)hydrazinyl]-4-[3-(pyrrolidin-1-ylsulfonyl)phenyl]-1,3-thiazole, N-[(Z)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine
| Molecular Formula | C22H24N4O4S2 |
|---|---|
| Molecular Weight | 472.12 g/mol |
| LogP | 4.0578 |
| Topological Polar Surface Area | 93.12 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 472.1239 |
| Heavy Atoms | 32 |
| Complexity | 1218.1737 |
Chemical Identifiers
| CAS Number | 577787-40-7 |
|---|---|
| SMILES | COC1=CC=CC(=C1OC)/C=N\NC2=NC(=CS2)C3=CC(=CC=C3)S(=O)(=O)N4CCCC4 |
Product Overview
N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine (CAS 577787-40-7), with molecular formula C22H24N4O4S2 and molecular weight 472.12 g/mol. IUPAC: N-[(Z)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine.
Chemical Property Profile of N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine
Property Insights of N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine
The XLogP value of 4.0578 indicates that N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 93.12 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine. Following Lipinski's Rule of Five, N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine?
The CAS number of N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine is 577787-40-7.
What is the molecular formula of N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine?
The molecular formula of N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine is C22H24N4O4S2.
What is the molecular weight of N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine?
The molecular weight of N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine is 472.12 g/mol.
Where can I buy N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine?
You can request a quote for N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine?
Yes, KEHONG BIO provides custom synthesis services for N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]-4-(3-pyrrolidin-1-ylsulfonylphenyl)-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.