(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide structure

(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide

TL;DR: (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide (CAS 577765-95-8) is a chemical compound with molecular formula C19H14ClFN8O2 and molecular weight 440.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-5-(4-methylphenyl)triazole-4-carboxamide

Also Known As: (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide, 1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-[(E)-(2-chloro-6-fluorophenyl)methylidene]-5-(4-methylphenyl)-1H-1,2,3-triazole-4-carbohydrazide, 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-5-(4-methylphenyl)triazole-4-carboxamide

CAS: 577765-95-8
Molecular Formula C19H14ClFN8O2
Molecular Weight 440.09 g/mol
LogP 2.76432
Topological Polar Surface Area 137.11 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 8
Rotatable Bonds 5
Exact Mass 440.09122
Heavy Atoms 31
Complexity 1262.3123

Chemical Identifiers

CAS Number 577765-95-8
SMILES CC1=CC=C(C=C1)C2=C(N=NN2C3=NON=C3N)C(=O)N/N=C/C4=C(C=CC=C4Cl)F

Product Overview

(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide (CAS 577765-95-8), with molecular formula C19H14ClFN8O2 and molecular weight 440.09 g/mol. IUPAC: 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-5-(4-methylphenyl)triazole-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide

XLogP
2.76432
TPSA (Topological Polar Surface Area)
137.11
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
8
Rotatable Bonds
5
Heavy Atoms
31
Complexity
1262.3123
Exact Mass
440.09122
Monoisotopic Mass
440.09122
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide

The XLogP value of 2.76432 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide. The TPSA of 137.11 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide. Following Lipinski's Rule of Five, (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

The CAS number of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide is 577765-95-8.

What is the molecular formula of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

The molecular formula of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide is C19H14ClFN8O2.

What is the molecular weight of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

The molecular weight of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide is 440.09 g/mol.

Where can I buy (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

You can request a quote for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

Yes, KEHONG BIO provides custom synthesis services for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(2-chloro-6-fluorobenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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