(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide structure

(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide

TL;DR: (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide (CAS 577765-47-0) is a chemical compound with molecular formula C19H16N8O3 and molecular weight 404.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(3-hydroxyphenyl)methylideneamino]-5-(4-methylphenyl)triazole-4-carboxamide

Also Known As: (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide, 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(3-hydroxyphenyl)methylideneamino]-5-(4-methylphenyl)triazole-4-carboxamide, 3-[(E)-(2-{[1-(4-ammonio-1,2,5-oxadiazol-3-yl)-5-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]carbonyl}hydrazinylidene)methyl]phenolate

CAS: 577765-47-0
Molecular Formula C19H16N8O3
Molecular Weight 404.13 g/mol
LogP 1.67742
Topological Polar Surface Area 157.34 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 9
Rotatable Bonds 5
Exact Mass 404.13452
Heavy Atoms 30
Complexity 1226.8228

Chemical Identifiers

CAS Number 577765-47-0
SMILES CC1=CC=C(C=C1)C2=C(N=NN2C3=NON=C3N)C(=O)N/N=C/C4=CC(=CC=C4)O

Product Overview

(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide (CAS 577765-47-0), with molecular formula C19H16N8O3 and molecular weight 404.13 g/mol. IUPAC: 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(3-hydroxyphenyl)methylideneamino]-5-(4-methylphenyl)triazole-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide

XLogP
1.67742
TPSA (Topological Polar Surface Area)
157.34
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
9
Rotatable Bonds
5
Heavy Atoms
30
Complexity
1226.8228
Exact Mass
404.13452
Monoisotopic Mass
404.13452
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide

The XLogP value of 1.67742 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide. The TPSA of 157.34 Ų indicates high polarity, suggesting (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

The CAS number of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide is 577765-47-0.

What is the molecular formula of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

The molecular formula of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide is C19H16N8O3.

What is the molecular weight of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

The molecular weight of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide is 404.13 g/mol.

Where can I buy (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

You can request a quote for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide?

Yes, KEHONG BIO provides custom synthesis services for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-hydroxybenzylidene)-5-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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