ATX inhibitor 10
TL;DR: ATX inhibitor 10 (CAS 577765-38-9) is a chemical compound with molecular formula C15H15Cl2N3OS and molecular weight 355.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(3,4-dichlorophenyl)methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one
Also Known As: ATX inhibitor 10, Disubstituted aryl-Me ATX inhibitor 3, Monosubstituted aryl-Me ATX inhibitor 5, (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, (5Z)-5-[(3,4-dichlorophenyl)methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one
| Molecular Formula | C15H15Cl2N3OS |
|---|---|
| Molecular Weight | 355.03 g/mol |
| LogP | 3.2111 |
| Topological Polar Surface Area | 35.91 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 355.03128 |
| Heavy Atoms | 22 |
| Complexity | 666.75146 |
Chemical Identifiers
| CAS Number | 577765-38-9 |
|---|---|
| SMILES | CN1CCN(CC1)C2=NC(=O)/C(=C/C3=CC(=C(C=C3)Cl)Cl)/S2 |
Product Overview
ATX inhibitor 10 (CAS 577765-38-9), with molecular formula C15H15Cl2N3OS and molecular weight 355.03 g/mol. IUPAC: (5Z)-5-[(3,4-dichlorophenyl)methylidene]-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-one.
Chemical Property Profile of ATX inhibitor 10
Property Insights of ATX inhibitor 10
The XLogP value of 3.2111 indicates that ATX inhibitor 10 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.91 Ų, ATX inhibitor 10 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, ATX inhibitor 10 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of ATX inhibitor 10?
The CAS number of ATX inhibitor 10 is 577765-38-9.
What is the molecular formula of ATX inhibitor 10?
The molecular formula of ATX inhibitor 10 is C15H15Cl2N3OS.
What is the molecular weight of ATX inhibitor 10?
The molecular weight of ATX inhibitor 10 is 355.03 g/mol.
Where can I buy ATX inhibitor 10?
You can request a quote for ATX inhibitor 10 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for ATX inhibitor 10?
Yes, KEHONG BIO provides custom synthesis services for ATX inhibitor 10 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.