A3281/0139590 structure

A3281/0139590

TL;DR: A3281/0139590 (CAS 577698-91-0) is a chemical compound with molecular formula C22H18F4N2O3S and molecular weight 466.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[1-(4-fluorophenyl)-6,6-dimethyl-2,4-dioxo-3-(trifluoromethyl)-5,7-dihydroindol-3-yl]thiophene-2-carboxamide

Also Known As: A3281/0139590, N-[1-(4-fluorophenyl)-6,6-dimethyl-2,4-dioxo-3-(trifluoromethyl)-2,3,4,5,6,7-hexahydro-1H-indol-3-yl]thiophene-2-carboxamide, N-(1-(4-fluorophenyl)-6,6-dimethyl-2,4-dioxo-3-(trifluoromethyl)-2,3,4,5,6,7-hexahydro-1H-indol-3-yl)thiophene-2-carboxamide, N-[1-(4-fluorophenyl)-6,6-dimethyl-2,4-dioxo-3-(trifluoromethyl)-5,7-dihydroindol-3-yl]thiophene-2-carboxamide

CAS: 577698-91-0
Molecular Formula C22H18F4N2O3S
Molecular Weight 466.10 g/mol
LogP 4.6081
Topological Polar Surface Area 66.48 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 466.0974
Heavy Atoms 32
Complexity 1136.9258

Chemical Identifiers

CAS Number 577698-91-0
SMILES CC1(CC2=C(C(=O)C1)C(C(=O)N2C3=CC=C(C=C3)F)(C(F)(F)F)NC(=O)C4=CC=CS4)C

Product Overview

A3281/0139590 (CAS 577698-91-0), with molecular formula C22H18F4N2O3S and molecular weight 466.10 g/mol. IUPAC: N-[1-(4-fluorophenyl)-6,6-dimethyl-2,4-dioxo-3-(trifluoromethyl)-5,7-dihydroindol-3-yl]thiophene-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of A3281/0139590

XLogP
4.6081
TPSA (Topological Polar Surface Area)
66.48
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
32
Complexity
1136.9258
Exact Mass
466.0974
Monoisotopic Mass
466.0974
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of A3281/0139590

The XLogP value of 4.6081 indicates that A3281/0139590 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.48 Ų falls within the moderate polarity range, balancing permeability and solubility for A3281/0139590. Following Lipinski's Rule of Five, A3281/0139590 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of A3281/0139590?

The CAS number of A3281/0139590 is 577698-91-0.

What is the molecular formula of A3281/0139590?

The molecular formula of A3281/0139590 is C22H18F4N2O3S.

What is the molecular weight of A3281/0139590?

The molecular weight of A3281/0139590 is 466.10 g/mol.

Where can I buy A3281/0139590?

You can request a quote for A3281/0139590 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for A3281/0139590?

Yes, KEHONG BIO provides custom synthesis services for A3281/0139590 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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