Sequifenadine
TL;DR: Sequifenadine (CAS 57734-69-7) is a chemical compound with molecular formula C22H27NO and molecular weight 321.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-azabicyclo[2.2.2]octan-3-yl-bis(2-methylphenyl)methanol
Also Known As: Sequifenadine, Sequifenadina, Sequifenadinum, Bicarphene, Sequifenadine [INN]
| Molecular Formula | C22H27NO |
|---|---|
| Molecular Weight | 321.21 g/mol |
| LogP | 4.1 |
| Topological Polar Surface Area | 23.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 321.20926 |
| Heavy Atoms | 24 |
| Complexity | 406.0 |
Chemical Identifiers
| CAS Number | 57734-69-7 |
|---|---|
| SMILES | CC1=CC=CC=C1C(C2CN3CCC2CC3)(C4=CC=CC=C4C)O |
| InChIKey | OXDOWGVJMITMJL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Sequifenadine (CAS 57734-69-7), with molecular formula C22H27NO and molecular weight 321.21 g/mol. IUPAC: 1-azabicyclo[2.2.2]octan-3-yl-bis(2-methylphenyl)methanol.
Chemical Property Profile of Sequifenadine
Property Insights of Sequifenadine
The XLogP value of 4.1 indicates that Sequifenadine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.5 Ų, Sequifenadine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Sequifenadine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Sequifenadine?
The CAS number of Sequifenadine is 57734-69-7.
What is the molecular formula of Sequifenadine?
The molecular formula of Sequifenadine is C22H27NO.
What is the molecular weight of Sequifenadine?
The molecular weight of Sequifenadine is 321.21 g/mol.
Where can I buy Sequifenadine?
You can request a quote for Sequifenadine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Sequifenadine?
Yes, KEHONG BIO provides custom synthesis services for Sequifenadine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.