Estradiol bis(tert-butyldimethylsilyl)ether
TL;DR: Estradiol bis(tert-butyldimethylsilyl)ether (CAS 57711-41-8) is a chemical compound with molecular formula C30H52O2Si2 and molecular weight 500.35 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
tert-butyl-[[(8R,9S,13S,14S,17S)-3-[tert-butyl(dimethyl)silyl]oxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]oxy]-dimethylsilane
Also Known As: Estradiol-btbdse, estradiolbis ether, A--estradiol di-TBDMS-ether, 17.beta.-Estradiol, bis-TBDMS, Estradiol bis(tert-butyldimethylsilyl)ether
| Molecular Formula | C30H52O2Si2 |
|---|---|
| Molecular Weight | 500.35 g/mol |
| LogP | 9.32 |
| Topological Polar Surface Area | 18.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 500.3506 |
| Heavy Atoms | 34 |
| Complexity | 733.0 |
Chemical Identifiers
| CAS Number | 57711-41-8 |
|---|---|
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O[Si](C)(C)C(C)(C)C)CCC4=C3C=CC(=C4)O[Si](C)(C)C(C)(C)C |
| InChIKey | JFLALYDXWVIVJI-KACYJRNJSA-N |
Product Overview
Estradiol bis(tert-butyldimethylsilyl)ether (CAS 57711-41-8), with molecular formula C30H52O2Si2 and molecular weight 500.35 g/mol. IUPAC: tert-butyl-[[(8R,9S,13S,14S,17S)-3-[tert-butyl(dimethyl)silyl]oxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]oxy]-dimethylsilane.
Chemical Property Profile of Estradiol bis(tert-butyldimethylsilyl)ether
Property Insights of Estradiol bis(tert-butyldimethylsilyl)ether
The XLogP value of 9.32 indicates that Estradiol bis(tert-butyldimethylsilyl)ether is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 18.5 Ų, Estradiol bis(tert-butyldimethylsilyl)ether exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Estradiol bis(tert-butyldimethylsilyl)ether has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Estradiol bis(tert-butyldimethylsilyl)ether?
The CAS number of Estradiol bis(tert-butyldimethylsilyl)ether is 57711-41-8.
What is the molecular formula of Estradiol bis(tert-butyldimethylsilyl)ether?
The molecular formula of Estradiol bis(tert-butyldimethylsilyl)ether is C30H52O2Si2.
What is the molecular weight of Estradiol bis(tert-butyldimethylsilyl)ether?
The molecular weight of Estradiol bis(tert-butyldimethylsilyl)ether is 500.35 g/mol.
Where can I buy Estradiol bis(tert-butyldimethylsilyl)ether?
You can request a quote for Estradiol bis(tert-butyldimethylsilyl)ether directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Estradiol bis(tert-butyldimethylsilyl)ether?
Yes, KEHONG BIO provides custom synthesis services for Estradiol bis(tert-butyldimethylsilyl)ether and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.