(E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one
TL;DR: (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one (CAS 57427-95-9) is a chemical compound with molecular formula C18H15NO2 and molecular weight 277.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-4-[1-(4-methylphenyl)ethylidene]-2-phenyl-1,3-oxazol-5-one
Also Known As: J3.138.728K, (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one, 2-phenyl-4-((E)-1-p-tolyl-ethylidene)-4H-oxazol-5-one, 4-[1-(4-Methylphenyl)ethylidene]-2-phenyloxazole-5(4H)-one, E-2-phenyl-4-(
| Molecular Formula | C18H15NO2 |
|---|---|
| Molecular Weight | 277.11 g/mol |
| LogP | 3.72962 |
| Topological Polar Surface Area | 38.66 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 277.1103 |
| Heavy Atoms | 21 |
| Complexity | 740.5476 |
Chemical Identifiers
| CAS Number | 57427-95-9 |
|---|---|
| SMILES | CC1=CC=C(C=C1)/C(=C/2\C(=O)OC(=N2)C3=CC=CC=C3)/C |
Product Overview
(E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one (CAS 57427-95-9), with molecular formula C18H15NO2 and molecular weight 277.11 g/mol. IUPAC: (4E)-4-[1-(4-methylphenyl)ethylidene]-2-phenyl-1,3-oxazol-5-one.
Chemical Property Profile of (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one
Property Insights of (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one
The XLogP value of 3.72962 indicates that (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.66 Ų, (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one?
The CAS number of (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one is 57427-95-9.
What is the molecular formula of (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one?
The molecular formula of (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one is C18H15NO2.
What is the molecular weight of (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one?
The molecular weight of (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one is 277.11 g/mol.
Where can I buy (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one?
You can request a quote for (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-Phenyl-4-(1-(p-tolyl)ethylidene)oxazol-5(4H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.