8-methyl-6-thioguanine
TL;DR: 8-methyl-6-thioguanine (CAS 57379-36-9) is a chemical compound with molecular formula C6H7N5S and molecular weight 181.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-amino-8-methyl-3,7-dihydropurine-6-thione
Also Known As: 8-methyl-6-thioguanine, 2-amino-8-methyl-9H-purin-6-thiol, 2-amino-8-methyl-3,7-dihydropurine-6-thione, 2-amino-8-methyl-9H-purine-6-thiol, 2-Amino-8-methyl-3,7-dihydro-6H-purine-6-thione
| Molecular Formula | C6H7N5S |
|---|---|
| Molecular Weight | 181.04 g/mol |
| LogP | 0.90611 |
| Topological Polar Surface Area | 83.38 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 0 |
| Exact Mass | 181.04222 |
| Heavy Atoms | 12 |
| Complexity | 482.13437 |
Chemical Identifiers
| CAS Number | 57379-36-9 |
|---|---|
| SMILES | CC1=NC2=C(N1)C(=S)N=C(N2)N |
Product Overview
8-methyl-6-thioguanine (CAS 57379-36-9), with molecular formula C6H7N5S and molecular weight 181.04 g/mol. IUPAC: 2-amino-8-methyl-3,7-dihydropurine-6-thione.
Chemical Property Profile of 8-methyl-6-thioguanine
Property Insights of 8-methyl-6-thioguanine
The XLogP value of 0.90611 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-methyl-6-thioguanine. The TPSA of 83.38 Ų falls within the moderate polarity range, balancing permeability and solubility for 8-methyl-6-thioguanine. Following Lipinski's Rule of Five, 8-methyl-6-thioguanine has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-methyl-6-thioguanine?
The CAS number of 8-methyl-6-thioguanine is 57379-36-9.
What is the molecular formula of 8-methyl-6-thioguanine?
The molecular formula of 8-methyl-6-thioguanine is C6H7N5S.
What is the molecular weight of 8-methyl-6-thioguanine?
The molecular weight of 8-methyl-6-thioguanine is 181.04 g/mol.
Where can I buy 8-methyl-6-thioguanine?
You can request a quote for 8-methyl-6-thioguanine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-methyl-6-thioguanine?
Yes, KEHONG BIO provides custom synthesis services for 8-methyl-6-thioguanine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.