(E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate
TL;DR: (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate (CAS 573707-18-3) is a chemical compound with molecular formula C22H22N2O5 and molecular weight 394.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 3-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]-1H-indole-2-carboxylate
Also Known As: (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate, ETHYL 3-[(2E)-3-(3,4-DIMETHOXYPHENYL)PROP-2-ENAMIDO]-1H-INDOLE-2-CARBOXYLATE, ethyl 3-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]-1H-indole-2-carboxylate, ethyl 3-{[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino}-1H-indole-2-carboxylate
| Molecular Formula | C22H22N2O5 |
|---|---|
| Molecular Weight | 394.15 g/mol |
| LogP | 4.0137 |
| Topological Polar Surface Area | 89.65 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 394.15286 |
| Heavy Atoms | 29 |
| Complexity | 1068.2499 |
Chemical Identifiers
| CAS Number | 573707-18-3 |
|---|---|
| SMILES | CCOC(=O)C1=C(C2=CC=CC=C2N1)NC(=O)/C=C/C3=CC(=C(C=C3)OC)OC |
Product Overview
(E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate (CAS 573707-18-3), with molecular formula C22H22N2O5 and molecular weight 394.15 g/mol. IUPAC: ethyl 3-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]-1H-indole-2-carboxylate.
Chemical Property Profile of (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate
Property Insights of (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate
The XLogP value of 4.0137 indicates that (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 89.65 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate. Following Lipinski's Rule of Five, (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate?
The CAS number of (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate is 573707-18-3.
What is the molecular formula of (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate?
The molecular formula of (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate is C22H22N2O5.
What is the molecular weight of (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate?
The molecular weight of (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate is 394.15 g/mol.
Where can I buy (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate?
You can request a quote for (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for (E)-ethyl 3-(3-(3,4-dimethoxyphenyl)acrylamido)-1H-indole-2-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.