![2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide structure](/static/products/5737/5737-11-1.webp)
2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide
TL;DR: 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide (CAS 5737-11-1) is a chemical compound with molecular formula C16H10ClF5N4O2S and molecular weight 452.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide
Also Known As: 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide, 2-{[8-Chloro-6-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl}-N-[2-(difluoromethoxy)phenyl]acetamide
| Molecular Formula | C16H10ClF5N4O2S |
|---|---|
| Molecular Weight | 452.01 g/mol |
| LogP | 4.7337 |
| Topological Polar Surface Area | 68.52 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 452.0133 |
| Heavy Atoms | 29 |
| Complexity | 1043.8123 |
Chemical Identifiers
| CAS Number | 5737-11-1 |
|---|---|
| SMILES | C1=CC=C(C(=C1)NC(=O)CSC2=NN=C3N2C=C(C=C3Cl)C(F)(F)F)OC(F)F |
Product Overview
2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide (CAS 5737-11-1), with molecular formula C16H10ClF5N4O2S and molecular weight 452.01 g/mol. IUPAC: 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide.
Chemical Property Profile of 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide
Property Insights of 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide
The XLogP value of 4.7337 indicates that 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.52 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide. Following Lipinski's Rule of Five, 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide?
The CAS number of 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide is 5737-11-1.
What is the molecular formula of 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide?
The molecular formula of 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide is C16H10ClF5N4O2S.
What is the molecular weight of 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide?
The molecular weight of 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide is 452.01 g/mol.
Where can I buy 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide?
You can request a quote for 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide?
Yes, KEHONG BIO provides custom synthesis services for 2-[[8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-N-[2-(difluoromethoxy)phenyl]acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.