Tadalafil Impurity 205 structure

Tadalafil Impurity 205

TL;DR: Tadalafil Impurity 205 (CAS 57223-16-2) is a chemical compound with molecular formula C8H9N3O and molecular weight 163.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-ethoxybenzotriazole

Also Known As: 1-ethoxybenzotriazole, Tadalafil Impurity 205, 1-Ethoxy-1H-1,2,3-benzotriazole, 1-ethoxy-1H-benzo[d][1,2,3]triazole

CAS: 57223-16-2
Molecular Formula C8H9N3O
Molecular Weight 163.07 g/mol
LogP 1.9
Topological Polar Surface Area 39.9 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 163.07455
Heavy Atoms 12
Complexity 153.0

Chemical Identifiers

CAS Number 57223-16-2
SMILES CCON1C2=CC=CC=C2N=N1
InChIKey MFDNDZUYLWWADX-UHFFFAOYSA-N

Product Overview

Tadalafil Impurity 205 (CAS 57223-16-2), with molecular formula C8H9N3O and molecular weight 163.07 g/mol. IUPAC: 1-ethoxybenzotriazole.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tadalafil Impurity 205

XLogP
1.9
TPSA (Topological Polar Surface Area)
39.9
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
12
Complexity
153.0
Exact Mass
163.07455
Monoisotopic Mass
163.07455
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tadalafil Impurity 205

The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tadalafil Impurity 205. With a topological polar surface area (TPSA) of 39.9 Ų, Tadalafil Impurity 205 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tadalafil Impurity 205 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tadalafil Impurity 205?

The CAS number of Tadalafil Impurity 205 is 57223-16-2.

What is the molecular formula of Tadalafil Impurity 205?

The molecular formula of Tadalafil Impurity 205 is C8H9N3O.

What is the molecular weight of Tadalafil Impurity 205?

The molecular weight of Tadalafil Impurity 205 is 163.07 g/mol.

Where can I buy Tadalafil Impurity 205?

You can request a quote for Tadalafil Impurity 205 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tadalafil Impurity 205?

Yes, KEHONG BIO provides custom synthesis services for Tadalafil Impurity 205 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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