Naftopidil hydrochloride
TL;DR: Naftopidil hydrochloride (CAS 57149-08-3) is a chemical compound with molecular formula C24H29ClN2O3 and molecular weight 428.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol;hydrochloride
Also Known As: NAFTOPIDIL HYDROCHLORIDE, KT-611 hydrochloride, Naftopidil (hydrochloride), NAFTOPIDIL DIHYDROCHLORIDE, 57149-07-2 (free base)
| Molecular Formula | C24H29ClN2O3 |
|---|---|
| Molecular Weight | 428.19 g/mol |
| LogP | 3.8321 |
| Topological Polar Surface Area | 45.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 428.18668 |
| Heavy Atoms | 30 |
| Complexity | 939.14215 |
Chemical Identifiers
| CAS Number | 57149-08-3 |
|---|---|
| SMILES | COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O.Cl |
Product Overview
Naftopidil hydrochloride (CAS 57149-08-3), with molecular formula C24H29ClN2O3 and molecular weight 428.19 g/mol. IUPAC: 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol;hydrochloride.
Chemical Property Profile of Naftopidil hydrochloride
Property Insights of Naftopidil hydrochloride
The XLogP value of 3.8321 indicates that Naftopidil hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.17 Ų, Naftopidil hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Naftopidil hydrochloride has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Naftopidil hydrochloride?
The CAS number of Naftopidil hydrochloride is 57149-08-3.
What is the molecular formula of Naftopidil hydrochloride?
The molecular formula of Naftopidil hydrochloride is C24H29ClN2O3.
What is the molecular weight of Naftopidil hydrochloride?
The molecular weight of Naftopidil hydrochloride is 428.19 g/mol.
Where can I buy Naftopidil hydrochloride?
You can request a quote for Naftopidil hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Naftopidil hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Naftopidil hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.