萘哌地尔
TL;DR: 萘哌地尔 (CAS 57149-07-2) is a chemical compound with molecular formula C24H28N2O3 and molecular weight 392.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
萘哌地尔
1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol
Also Known As: naftopidil, Flivas, Avishot, Naftopidilum, Naftopidil [INN]
| Molecular Formula | C24H28N2O3 |
|---|---|
| Molecular Weight | 392.21 g/mol |
| LogP | 4.1 |
| Topological Polar Surface Area | 45.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 392.21 |
| Heavy Atoms | 29 |
| Complexity | 483.0 |
Chemical Identifiers
| CAS Number | 57149-07-2 |
|---|---|
| SMILES | COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O |
| InChIKey | HRRBJVNMSRJFHQ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
萘哌地尔 (CAS 57149-07-2), with molecular formula C24H28N2O3 and molecular weight 392.21 g/mol. IUPAC: 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol.
Chemical Property Profile of 萘哌地尔
Property Insights of 萘哌地尔
The XLogP value of 4.1 indicates that Naftopidil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.2 Ų, 萘哌地尔 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Naftopidil has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Naftopidil?
The CAS number of Naftopidil is 57149-07-2.
What is the molecular formula of Naftopidil?
The molecular formula of Naftopidil is C24H28N2O3.
What is the molecular weight of Naftopidil?
The molecular weight of Naftopidil is 392.21 g/mol.
Where can I buy Naftopidil?
You can request a quote for Naftopidil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Naftopidil?
Yes, KEHONG BIO provides custom synthesis services for Naftopidil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.