Moduretic structure

Moduretic

TL;DR: Moduretic (CAS 57017-78-4) is a chemical compound with molecular formula C13H17Cl3N10O5S2 and molecular weight 561.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide;3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride

Also Known As: Moduretic, Amilco, Hypertane, Ameride, Amitrid

CAS: 57017-78-4
Molecular Formula C13H17Cl3N10O5S2
Molecular Weight 561.99 g/mol
LogP -1.2215
Topological Polar Surface Area 294.0 Ų
Hydrogen Bond Donors 8
Hydrogen Bond Acceptors 12
Rotatable Bonds 2
Exact Mass 561.989
Heavy Atoms 33
Complexity 773.0

Chemical Identifiers

CAS Number 57017-78-4
SMILES C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl.C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.Cl
InChIKey QRDAGKVHMGNVHB-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (16 patents)

Product Overview

Moduretic (CAS 57017-78-4), with molecular formula C13H17Cl3N10O5S2 and molecular weight 561.99 g/mol. IUPAC: 6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide;3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Moduretic

XLogP
-1.2215
TPSA (Topological Polar Surface Area)
294.0
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
12
Rotatable Bonds
2
Heavy Atoms
33
Complexity
773.0
Exact Mass
561.989
Monoisotopic Mass
561.989
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Moduretic

The XLogP value of -1.2215 indicates that Moduretic is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 294.0 Ų indicates high polarity, suggesting Moduretic may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Moduretic has 8 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Moduretic?

The CAS number of Moduretic is 57017-78-4.

What is the molecular formula of Moduretic?

The molecular formula of Moduretic is C13H17Cl3N10O5S2.

What is the molecular weight of Moduretic?

The molecular weight of Moduretic is 561.99 g/mol.

Where can I buy Moduretic?

You can request a quote for Moduretic directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Moduretic?

Yes, KEHONG BIO provides custom synthesis services for Moduretic and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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