美克洛嗪
TL;DR: 美克洛嗪 (CAS 569-65-3) is a chemical compound with molecular formula C25H27ClN2 and molecular weight 390.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
美克洛嗪
1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
Also Known As: meclizine, Meclozine, Parachloramine, Vomisseis, Navicalm
| Molecular Formula | C25H27ClN2 |
|---|---|
| Molecular Weight | 390.19 g/mol |
| LogP | 5.8 |
| Topological Polar Surface Area | 6.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 390.18628 |
| Heavy Atoms | 28 |
| Complexity | 447.0 |
| Melting Point | 217-224 |
| Boiling Point | 230 °C @ 2 MM HG |
| Solubility | 0.1g/100mL |
Chemical Identifiers
| CAS Number | 569-65-3 |
|---|---|
| SMILES | CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl |
| InChIKey | OCJYIGYOJCODJL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 21 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
美克洛嗪 (CAS 569-65-3), with molecular formula C25H27ClN2 and molecular weight 390.19 g/mol. IUPAC: 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine.
Chemical Property Profile of 美克洛嗪
Property Insights of 美克洛嗪
The XLogP value of 5.8 indicates that 美克洛嗪 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, 美克洛嗪 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 美克洛嗪 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 美克洛嗪?
The CAS number of 美克洛嗪 is 569-65-3.
What is the molecular formula of 美克洛嗪?
The molecular formula of 美克洛嗪 is C25H27ClN2.
What is the molecular weight of 美克洛嗪?
The molecular weight of 美克洛嗪 is 390.19 g/mol.
Where can I buy 美克洛嗪?
You can request a quote for 美克洛嗪 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 美克洛嗪?
Yes, KEHONG BIO provides custom synthesis services for 美克洛嗪 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.