27-hydroxycholesterol
TL;DR: 27-hydroxycholesterol (CAS 56845-83-1) is a chemical compound with molecular formula C27H46O2 and molecular weight 402.35 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
17-(7-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Also Known As: 27-hydroxycholesterol, 26-Hydroxycholesterol, (25s)-26-hydroxycholesterol, 27HC, 5-cholestene-3 beta,27-diol
| Molecular Formula | C27H46O2 |
|---|---|
| Molecular Weight | 402.35 g/mol |
| LogP | 7.1 |
| Topological Polar Surface Area | 40.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 402.3498 |
| Heavy Atoms | 29 |
| Complexity | 612.0 |
Chemical Identifiers
| CAS Number | 56845-83-1 |
|---|---|
| SMILES | CC(CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)CO |
| InChIKey | FYHRJWMENCALJY-UHFFFAOYSA-N |
Product Overview
27-hydroxycholesterol (CAS 56845-83-1), with molecular formula C27H46O2 and molecular weight 402.35 g/mol. IUPAC: 17-(7-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol.
Chemical Property Profile of 27-hydroxycholesterol
Property Insights of 27-hydroxycholesterol
The XLogP value of 7.1 indicates that 27-hydroxycholesterol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.5 Ų, 27-hydroxycholesterol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 27-hydroxycholesterol has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 27-hydroxycholesterol?
The CAS number of 27-hydroxycholesterol is 56845-83-1.
What is the molecular formula of 27-hydroxycholesterol?
The molecular formula of 27-hydroxycholesterol is C27H46O2.
What is the molecular weight of 27-hydroxycholesterol?
The molecular weight of 27-hydroxycholesterol is 402.35 g/mol.
Where can I buy 27-hydroxycholesterol?
You can request a quote for 27-hydroxycholesterol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 27-hydroxycholesterol?
Yes, KEHONG BIO provides custom synthesis services for 27-hydroxycholesterol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.