Puromycin Hydrochloride
TL;DR: Puromycin Hydrochloride (CAS 5682-30-4) is a chemical compound with molecular formula C22H31Cl2N7O5 and molecular weight 543.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;dihydrochloride
Also Known As: Puromycin dihydrochloride, Puromycin hydrochloride, Puromycin 2HCl, puromycin, Puromycin diHCl
| Molecular Formula | C22H31Cl2N7O5 |
|---|---|
| Molecular Weight | 543.18 g/mol |
| LogP | 0.0499 |
| Topological Polar Surface Area | 161.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 8 |
| Exact Mass | 543.1764 |
| Heavy Atoms | 36 |
| Complexity | 680.0 |
Chemical Identifiers
| CAS Number | 5682-30-4 |
|---|---|
| SMILES | CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O.Cl.Cl |
| InChIKey | MKSVFGKWZLUTTO-FZFAUISWSA-N |
Patent-Derived Application Labels
Derived from 10 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Puromycin Hydrochloride (CAS 5682-30-4), with molecular formula C22H31Cl2N7O5 and molecular weight 543.18 g/mol. IUPAC: (2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;dihydrochloride.
Chemical Property Profile of Puromycin Hydrochloride
Property Insights of Puromycin Hydrochloride
The XLogP value of 0.0499 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Puromycin Hydrochloride. The TPSA of 161.0 Ų indicates high polarity, suggesting Puromycin Hydrochloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Puromycin Hydrochloride has 6 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Puromycin Hydrochloride?
The CAS number of Puromycin Hydrochloride is 5682-30-4.
What is the molecular formula of Puromycin Hydrochloride?
The molecular formula of Puromycin Hydrochloride is C22H31Cl2N7O5.
What is the molecular weight of Puromycin Hydrochloride?
The molecular weight of Puromycin Hydrochloride is 543.18 g/mol.
Where can I buy Puromycin Hydrochloride?
You can request a quote for Puromycin Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Puromycin Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Puromycin Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.