4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine
TL;DR: 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine (CAS 566149-73-3) is a chemical compound with molecular formula C8H5Cl2N3S and molecular weight 244.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2,5-dichlorothiophen-3-yl)pyrimidin-2-amine
Also Known As: 1pxi, 4-(2,5-dichlorothiophen-3-yl)pyrimidin-2-amine, 4-(2,5-DICHLOROTHIEN-3-YL)PYRIMIDIN-2-AMINE, 4-(2,5-DICHLORO-THIOPHEN-3-YL)-PYRIMIDIN-2-YLAMINE, 4-(2,5-dichloro-3-thienyl)-2-pyrimidinamine
| Molecular Formula | C8H5Cl2N3S |
|---|---|
| Molecular Weight | 244.96 g/mol |
| LogP | 3.1 |
| Topological Polar Surface Area | 80.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 244.95813 |
| Heavy Atoms | 14 |
| Complexity | 207.0 |
Chemical Identifiers
| CAS Number | 566149-73-3 |
|---|---|
| SMILES | C1=CN=C(N=C1C2=C(SC(=C2)Cl)Cl)N |
| InChIKey | PAPYICJQRHSQGK-UHFFFAOYSA-N |
Product Overview
4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine (CAS 566149-73-3), with molecular formula C8H5Cl2N3S and molecular weight 244.96 g/mol. IUPAC: 4-(2,5-dichlorothiophen-3-yl)pyrimidin-2-amine.
Chemical Property Profile of 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine
Property Insights of 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine
The XLogP value of 3.1 indicates that 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine. Following Lipinski's Rule of Five, 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine?
The CAS number of 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine is 566149-73-3.
What is the molecular formula of 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine?
The molecular formula of 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine is C8H5Cl2N3S.
What is the molecular weight of 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine?
The molecular weight of 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine is 244.96 g/mol.
Where can I buy 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine?
You can request a quote for 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine?
Yes, KEHONG BIO provides custom synthesis services for 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.