![2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide structure](/static/products/5651/565165-72-2.webp)
2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide
TL;DR: 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide (CAS 565165-72-2) is a chemical compound with molecular formula C12H9ClF2N2OS and molecular weight 302.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]propanamide
Also Known As: 2-Chloro-N-[4-(3,4-difluoro-phenyl)-thiazol-2-yl]-propionamide, 2-chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]propanamide, 2-Chloro-N-(4-(3,4-difluorophenyl)thiazol-2-yl)propanamide, 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide, 2-Chloro-N-(4-(3,4-difluorophenyl)-2-thiazolyl)propanamide
| Molecular Formula | C12H9ClF2N2OS |
|---|---|
| Molecular Weight | 302.01 g/mol |
| LogP | 3.6541 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 302.00922 |
| Heavy Atoms | 19 |
| Complexity | 615.5269 |
Chemical Identifiers
| CAS Number | 565165-72-2 |
|---|---|
| SMILES | CC(C(=O)NC1=NC(=CS1)C2=CC(=C(C=C2)F)F)Cl |
Product Overview
2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide (CAS 565165-72-2), with molecular formula C12H9ClF2N2OS and molecular weight 302.01 g/mol. IUPAC: 2-chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]propanamide.
Chemical Property Profile of 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide
Property Insights of 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide
The XLogP value of 3.6541 indicates that 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide?
The CAS number of 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide is 565165-72-2.
What is the molecular formula of 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide?
The molecular formula of 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide is C12H9ClF2N2OS.
What is the molecular weight of 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide?
The molecular weight of 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide is 302.01 g/mol.
Where can I buy 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide?
You can request a quote for 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-N-[4-(3,4-difluorophenyl)-2-thiazolyl]propanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.