Malexil structure

Malexil

TL;DR: Malexil (CAS 56222-04-9) is a chemical compound with molecular formula C20H26ClNO2 and molecular weight 347.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3R,4S)-3-[(4-methoxyphenoxy)methyl]-1-methyl-4-phenylpiperidine;hydrochloride

Also Known As: Malexil, FEMOXETINE HYDROCHLORIDE, Femoxetine HCl, FEMOXETINE HYDROCHLORIDE [MI], FEMOXETINE HYDROCHLORIDE [WHO-DD]

CAS: 56222-04-9
Molecular Formula C20H26ClNO2
Molecular Weight 347.17 g/mol
LogP 4.2313
Topological Polar Surface Area 21.7 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 5
Exact Mass 347.1652
Heavy Atoms 24
Complexity 335.0

Chemical Identifiers

CAS Number 56222-04-9
SMILES CN1CC[C@@H]([C@H](C1)COC2=CC=C(C=C2)OC)C3=CC=CC=C3.Cl
InChIKey ORJNLCKHRRUOMU-OGPPPPIKSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (1 patents) Organic Building Blocks (1 patents) Pharmaceutical Intermediates (32 patents)

Product Overview

Malexil (CAS 56222-04-9), with molecular formula C20H26ClNO2 and molecular weight 347.17 g/mol. IUPAC: (3R,4S)-3-[(4-methoxyphenoxy)methyl]-1-methyl-4-phenylpiperidine;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Malexil

XLogP
4.2313
TPSA (Topological Polar Surface Area)
21.7
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
5
Heavy Atoms
24
Complexity
335.0
Exact Mass
347.1652
Monoisotopic Mass
347.1652
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Malexil

The XLogP value of 4.2313 indicates that Malexil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 21.7 Ų, Malexil exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Malexil has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Malexil?

The CAS number of Malexil is 56222-04-9.

What is the molecular formula of Malexil?

The molecular formula of Malexil is C20H26ClNO2.

What is the molecular weight of Malexil?

The molecular weight of Malexil is 347.17 g/mol.

Where can I buy Malexil?

You can request a quote for Malexil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Malexil?

Yes, KEHONG BIO provides custom synthesis services for Malexil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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