18-Hydroxycorticosterone
TL;DR: 18-Hydroxycorticosterone (CAS 561-65-9) is a chemical compound with molecular formula C21H30O5 and molecular weight 362.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-13-(hydroxymethyl)-10-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Also Known As: 18-HYDROXYCORTICOSTERONE, 18-hydroxy corticosterone, 18 Hydrocorticosterone, 18-Hydrocorticosterone, Hydroxycorticosterone, 18
| Molecular Formula | C21H30O5 |
|---|---|
| Molecular Weight | 362.21 g/mol |
| LogP | 0.7 |
| Topological Polar Surface Area | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 362.20932 |
| Heavy Atoms | 26 |
| Complexity | 655.0 |
Chemical Identifiers
| CAS Number | 561-65-9 |
|---|---|
| SMILES | C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)CO)O |
| InChIKey | HFSXHZZDNDGLQN-ZVIOFETBSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
18-Hydroxycorticosterone (CAS 561-65-9), with molecular formula C21H30O5 and molecular weight 362.21 g/mol. IUPAC: (8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-13-(hydroxymethyl)-10-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 18-Hydroxycorticosterone
Property Insights of 18-Hydroxycorticosterone
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 18-Hydroxycorticosterone. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 18-Hydroxycorticosterone. Following Lipinski's Rule of Five, 18-Hydroxycorticosterone has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 18-Hydroxycorticosterone?
The CAS number of 18-Hydroxycorticosterone is 561-65-9.
What is the molecular formula of 18-Hydroxycorticosterone?
The molecular formula of 18-Hydroxycorticosterone is C21H30O5.
What is the molecular weight of 18-Hydroxycorticosterone?
The molecular weight of 18-Hydroxycorticosterone is 362.21 g/mol.
Where can I buy 18-Hydroxycorticosterone?
You can request a quote for 18-Hydroxycorticosterone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 18-Hydroxycorticosterone?
Yes, KEHONG BIO provides custom synthesis services for 18-Hydroxycorticosterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.