(-)-Bicuculline
TL;DR: (-)-Bicuculline (CAS 56083-00-2) is a chemical compound with molecular formula C20H17NO6 and molecular weight 367.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6S)-6-[(5R)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
Also Known As: (-)-Bicuculline, dl-Bicuculline, bicuculline, (+-)-Bicuculline, (+/-)-BICUCULLINE
| Molecular Formula | C20H17NO6 |
|---|---|
| Molecular Weight | 367.11 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 66.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 367.1056 |
| Heavy Atoms | 27 |
| Complexity | 615.0 |
Chemical Identifiers
| CAS Number | 56083-00-2 |
|---|---|
| SMILES | CN1CCC2=CC3=C(C=C2[C@@H]1[C@@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3 |
| InChIKey | IYGYMKDQCDOMRE-MSOLQXFVSA-N |
Product Overview
(-)-Bicuculline (CAS 56083-00-2), with molecular formula C20H17NO6 and molecular weight 367.11 g/mol. IUPAC: (6S)-6-[(5R)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one.
Chemical Property Profile of (-)-Bicuculline
Property Insights of (-)-Bicuculline
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (-)-Bicuculline. The TPSA of 66.5 Ų falls within the moderate polarity range, balancing permeability and solubility for (-)-Bicuculline. Following Lipinski's Rule of Five, (-)-Bicuculline has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (-)-Bicuculline?
The CAS number of (-)-Bicuculline is 56083-00-2.
What is the molecular formula of (-)-Bicuculline?
The molecular formula of (-)-Bicuculline is C20H17NO6.
What is the molecular weight of (-)-Bicuculline?
The molecular weight of (-)-Bicuculline is 367.11 g/mol.
Where can I buy (-)-Bicuculline?
You can request a quote for (-)-Bicuculline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (-)-Bicuculline?
Yes, KEHONG BIO provides custom synthesis services for (-)-Bicuculline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.