尼卡地平
TL;DR: 尼卡地平 (CAS 55985-32-5) is a chemical compound with molecular formula C26H29N3O6 and molecular weight 479.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
尼卡地平
5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: nicardipine, Nicardipinum, Nicardipino, Perpidine, Cardene
| Molecular Formula | C26H29N3O6 |
|---|---|
| Molecular Weight | 479.21 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 114.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 10 |
| Exact Mass | 479.20563 |
| Heavy Atoms | 35 |
| Complexity | 856.0 |
| Melting Point | 136-138 °C |
| Solubility | 2.2 |
Chemical Identifiers
| CAS Number | 55985-32-5 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC |
| InChIKey | ZBBHBTPTTSWHBA-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 18 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
尼卡地平 (CAS 55985-32-5), with molecular formula C26H29N3O6 and molecular weight 479.21 g/mol. IUPAC: 5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of 尼卡地平
Property Insights of 尼卡地平
The XLogP value of 3.8 indicates that 尼卡地平 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 114.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 尼卡地平. Following Lipinski's Rule of Five, 尼卡地平 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 尼卡地平?
The CAS number of 尼卡地平 is 55985-32-5.
What is the molecular formula of 尼卡地平?
The molecular formula of 尼卡地平 is C26H29N3O6.
What is the molecular weight of 尼卡地平?
The molecular weight of 尼卡地平 is 479.21 g/mol.
Where can I buy 尼卡地平?
You can request a quote for 尼卡地平 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 尼卡地平?
Yes, KEHONG BIO provides custom synthesis services for 尼卡地平 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.