Antibiotic A447 B structure

Antibiotic A447 B

TL;DR: Antibiotic A447 B (CAS 55945-22-7) is a chemical compound with molecular formula C60H88N2O21 and molecular weight 1172.59 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7-[4-(dimethylamino)-5-[4-hydroxy-5-(5-hydroxy-6-methyloxan-2-yl)oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-10-[4-(dimethylamino)-5-[5-(5-hydroxy-6-methyloxan-2-yl)oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-9-ethyl-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione

Also Known As: Antibiotic A447 B, Cosmomycin C, Antibiotic A447-B, 7-[4-(dimethylamino)-5-[4-hydroxy-5-(5-hydroxy-6-methyloxan-2-yl)oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-10-[4-(dimethylamino)-5-[5-(5-hydroxy-6-methyloxan-2-yl)oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-9-ethyl-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione, 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-10-((O-2,3,6-trideoxy-alpha-L-threo-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-7-((O-2,3,6-trideoxy-alpha-L-threo-hexopyranosyl-(1-4)-O-2,3,6-trideoxy-alpha-L-threo-hexopyranosyl-(1-4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R-(7alpha,8beta,10beta))-

CAS: 55945-22-7
Molecular Formula C60H88N2O21
Molecular Weight 1172.59 g/mol
LogP 4.7026
Topological Polar Surface Area 292.99 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 23
Rotatable Bonds 15
Exact Mass 1172.588
Heavy Atoms 83
Complexity 2614.494

Chemical Identifiers

CAS Number 55945-22-7
SMILES CCC1(CC(C2=C(C1OC3CC(C(C(O3)C)OC4CCC(C(O4)C)OC5CCC(C(O5)C)O)N(C)C)C(=C6C(=C2O)C(=O)C7=C(C6=O)C=CC=C7O)O)OC8CC(C(C(O8)C)OC9CC(C(C(O9)C)OC1CCC(C(O1)C)O)O)N(C)C)O

Product Overview

Antibiotic A447 B (CAS 55945-22-7), with molecular formula C60H88N2O21 and molecular weight 1172.59 g/mol. IUPAC: 7-[4-(dimethylamino)-5-[4-hydroxy-5-(5-hydroxy-6-methyloxan-2-yl)oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-10-[4-(dimethylamino)-5-[5-(5-hydroxy-6-methyloxan-2-yl)oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-9-ethyl-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Antibiotic A447 B

XLogP
4.7026
TPSA (Topological Polar Surface Area)
292.99
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
23
Rotatable Bonds
15
Heavy Atoms
83
Complexity
2614.494
Exact Mass
1172.588
Monoisotopic Mass
1172.588
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Antibiotic A447 B

The XLogP value of 4.7026 indicates that Antibiotic A447 B is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 292.99 Ų indicates high polarity, suggesting Antibiotic A447 B may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Antibiotic A447 B has 7 hydrogen bond donor(s) and 23 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Antibiotic A447 B?

The CAS number of Antibiotic A447 B is 55945-22-7.

What is the molecular formula of Antibiotic A447 B?

The molecular formula of Antibiotic A447 B is C60H88N2O21.

What is the molecular weight of Antibiotic A447 B?

The molecular weight of Antibiotic A447 B is 1172.59 g/mol.

Where can I buy Antibiotic A447 B?

You can request a quote for Antibiotic A447 B directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Antibiotic A447 B?

Yes, KEHONG BIO provides custom synthesis services for Antibiotic A447 B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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