Metoclopramide dihydrochloride monohydrate structure

Metoclopramide dihydrochloride monohydrate

TL;DR: Metoclopramide dihydrochloride monohydrate (CAS 5581-45-3) is a chemical compound with molecular formula C14H26Cl3N3O3 and molecular weight 389.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrate;dihydrochloride

Also Known As: Metadrate, Gastronerton, Primperan, Emetid, Reglan

CAS: 5581-45-3
Molecular Formula C14H26Cl3N3O3
Molecular Weight 389.10 g/mol
LogP 2.0213
Topological Polar Surface Area 68.6 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 5
Rotatable Bonds 7
Exact Mass 389.10397
Heavy Atoms 23
Complexity 300.0

Chemical Identifiers

CAS Number 5581-45-3
SMILES CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl.O.Cl.Cl
InChIKey IRQVJPHZDYMXNW-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (5 patents) Pharmaceutical Intermediates (5 patents)

Product Overview

Metoclopramide dihydrochloride monohydrate (CAS 5581-45-3), with molecular formula C14H26Cl3N3O3 and molecular weight 389.10 g/mol. IUPAC: 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrate;dihydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Metoclopramide dihydrochloride monohydrate

XLogP
2.0213
TPSA (Topological Polar Surface Area)
68.6
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
5
Rotatable Bonds
7
Heavy Atoms
23
Complexity
300.0
Exact Mass
389.10397
Monoisotopic Mass
389.10397
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Metoclopramide dihydrochloride monohydrate

The XLogP value of 2.0213 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Metoclopramide dihydrochloride monohydrate. The TPSA of 68.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Metoclopramide dihydrochloride monohydrate. Following Lipinski's Rule of Five, Metoclopramide dihydrochloride monohydrate has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Metoclopramide dihydrochloride monohydrate?

The CAS number of Metoclopramide dihydrochloride monohydrate is 5581-45-3.

What is the molecular formula of Metoclopramide dihydrochloride monohydrate?

The molecular formula of Metoclopramide dihydrochloride monohydrate is C14H26Cl3N3O3.

What is the molecular weight of Metoclopramide dihydrochloride monohydrate?

The molecular weight of Metoclopramide dihydrochloride monohydrate is 389.10 g/mol.

Where can I buy Metoclopramide dihydrochloride monohydrate?

You can request a quote for Metoclopramide dihydrochloride monohydrate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Metoclopramide dihydrochloride monohydrate?

Yes, KEHONG BIO provides custom synthesis services for Metoclopramide dihydrochloride monohydrate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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