Orexin structure

Orexin

TL;DR: Orexin (CAS 55661-66-0) is a chemical compound with molecular formula C14H12N2 and molecular weight 208.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-phenyl-1,2-dihydroquinazoline

Also Known As: Orexin, phenyldihydrochinazoline, 2-phenyl-1,2-dihydroquinazoline, 1,2-Dihydro-2-phenylquinazoline, J1.867.464E

CAS: 55661-66-0
Molecular Formula C14H12N2
Molecular Weight 208.10 g/mol
LogP 3.2298
Topological Polar Surface Area 24.39 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 208.10005
Heavy Atoms 16
Complexity 517.2684

Chemical Identifiers

CAS Number 55661-66-0
SMILES C1=CC=C(C=C1)C2NC3=CC=CC=C3C=N2

Product Overview

Orexin (CAS 55661-66-0), with molecular formula C14H12N2 and molecular weight 208.10 g/mol. IUPAC: 2-phenyl-1,2-dihydroquinazoline.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Orexin

XLogP
3.2298
TPSA (Topological Polar Surface Area)
24.39
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
16
Complexity
517.2684
Exact Mass
208.10005
Monoisotopic Mass
208.10005
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Orexin

The XLogP value of 3.2298 indicates that Orexin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 24.39 Ų, Orexin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Orexin has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Orexin?

The CAS number of Orexin is 55661-66-0.

What is the molecular formula of Orexin?

The molecular formula of Orexin is C14H12N2.

What is the molecular weight of Orexin?

The molecular weight of Orexin is 208.10 g/mol.

Where can I buy Orexin?

You can request a quote for Orexin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Orexin?

Yes, KEHONG BIO provides custom synthesis services for Orexin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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