2'-Epi-9,10-dihydroergotamine structure

2'-Epi-9,10-dihydroergotamine

TL;DR: 2'-Epi-9,10-dihydroergotamine (CAS 5550-75-4) is a chemical compound with molecular formula C33H37N5O5 and molecular weight 583.28 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(6aR,9R,10aR)-N-[(1S,2S,4S,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

Also Known As: 2'-Epidihydroergotamine, 2'-Epi-9,10-dihydroergotamine, 2a(2)-Epidihydroergotamine, (2'ss,5'a)-9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione; Aciergotamine, dihydro- (6CI,7CI); 2'-Epidihydroergotamine; Aci-Dihydroergotamine; (6aR,9R,10aR)-N-[(2S,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9,10,10aoctahydroindolo[4,3-fg]quinoline-9-carboxamide; 2'-epi-9,10-dihydroergotamine; Dihydroergotamine Mesilate Imp. D (EP), 5'alpha-Benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-2'beta,10alpha-9,10-dihydroergotaman

CAS: 5550-75-4
Molecular Formula C33H37N5O5
Molecular Weight 583.28 g/mol
LogP 2.0811
Topological Polar Surface Area 118.21 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 583.2795
Heavy Atoms 43
Complexity 1640.7913

Chemical Identifiers

CAS Number 5550-75-4
SMILES C[C@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@@H]5C[C@H]6[C@@H](CC7=CNC8=CC=CC6=C78)N(C5)C

Product Overview

2'-Epi-9,10-dihydroergotamine (CAS 5550-75-4), with molecular formula C33H37N5O5 and molecular weight 583.28 g/mol. IUPAC: (6aR,9R,10aR)-N-[(1S,2S,4S,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2'-Epi-9,10-dihydroergotamine

XLogP
2.0811
TPSA (Topological Polar Surface Area)
118.21
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
43
Complexity
1640.7913
Exact Mass
583.2795
Monoisotopic Mass
583.2795
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2'-Epi-9,10-dihydroergotamine

The XLogP value of 2.0811 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2'-Epi-9,10-dihydroergotamine. The TPSA of 118.21 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-Epi-9,10-dihydroergotamine. Following Lipinski's Rule of Five, 2'-Epi-9,10-dihydroergotamine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2'-Epi-9,10-dihydroergotamine?

The CAS number of 2'-Epi-9,10-dihydroergotamine is 5550-75-4.

What is the molecular formula of 2'-Epi-9,10-dihydroergotamine?

The molecular formula of 2'-Epi-9,10-dihydroergotamine is C33H37N5O5.

What is the molecular weight of 2'-Epi-9,10-dihydroergotamine?

The molecular weight of 2'-Epi-9,10-dihydroergotamine is 583.28 g/mol.

Where can I buy 2'-Epi-9,10-dihydroergotamine?

You can request a quote for 2'-Epi-9,10-dihydroergotamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2'-Epi-9,10-dihydroergotamine?

Yes, KEHONG BIO provides custom synthesis services for 2'-Epi-9,10-dihydroergotamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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